Abstract Proceedings of IESMDT - 2021
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THE CREATION, CHARACTERIZATION, AND BIOLOGICAL ACTIVITY OF COPPER (II) COMPLEXES AND HYDRAZONES
There are many different biological activity pathways for copper due to the metal's fundamental role as a redox-active component of various metabolic enzymes. Potent antiproliferative, antibacterial, nuclease, anti-inflammatory, and antimycobacterial actions are known to be displayed by copper (II) coordination compounds. Hydrazones are chemical ligands with antibacterial, antiviral, and antifungal characteristics that are frequently utilized for complexation with copper (II). The improved pharmacological activity of the system may be caused by copper-ligand interaction, which may promote charge delocalization and increase net hydrophobicity of the system. Hydrazone, nitrofurantoin, and ftivazide are coordination compounds of Cu(II) with 4,6-di-tert-butyl-2,3-dihydroxybenzaldehyde that have been synthesized, characterized using elemental and XRD analysis, FT-IR, UV-Vis, and NMR spectroscopy, and tested for antibacterial activity on Gram-positive and Gram-negative bacteria in vitro.
Hydrazones; copper (II) complexes; antibacterial activity
17/09/2021
141
IESMDT139
IMPORTANT DAYS
Paper Submission Last Date
September 27th, 2025
Notification of Acceptance
October 25th, 2025
Camera Ready Paper Submission & Author's Registration
November 11th, 2025
Date of Conference
November 28th, 2025